pyOpenSSL uses distutils, so there really shouldn't be any problems. To build the library:
python setup.py build
If your OpenSSL header files aren't in /usr/include, you may need to
supply the -I flag to let the setup script know where to look. The same
goes for the libraries of course, use the -L flag. Note that
build won't accept these flags, so you have to run first
build_ext and then build! Example:
python setup.py build_ext -I/usr/local/ssl/include -L/usr/local/ssl/lib python setup.py build
Now you should have a directory called OpenSSL that contains e.g.
SSL.so and __init__.py somewhere in the build dicrectory,
so just:
python setup.py install
If you, for some arcane reason, don't want the module to appear in the
site-packages directory, use the --prefix option.
You can, of course, do
python setup.py --help
to find out more about how to use the script.